The Canada Brief

Tech · 10 d ago

A syringe and vial for an injection

A personalized mRNA vaccine cuts the risk of melanoma recurrence by 42 per cent

Vaccine and drug

82.2% recurrence-free

Drug alone

70% recurrence-free

At the end of follow-up, 82.2 per cent of patients who got both treatments were recurrence-free, against 70 per cent on the immunotherapy drug alone.

The Phase 3 trial by Merck and Moderna followed 1,137 people with high-risk melanoma whose tumours had been removed, for an average of 24.6 months.

What we know

  • 42% lower risk of recurrence or death
  • Mild side effects: fever, fatigue, pain

Not yet

  • Approval by health authorities
  • Whether it can scale affordably

The vaccine is still under investigation and needs approval from health authorities before wide use.